Recombinant Mouse Rorb Protein, Myc/DDK-tagged

• Cat.No.: Rorb-5575M
• Product Overview: Purified recombinant protein of mouse full-length RAR-related orphan receptor beta (cDNA clone MGC:38728 IMAGE:5358124), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 43.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rorb RAR-related orphan receptor beta [ Mus musculus (house mouse) ]
• Official Symbol: Rorb
• Synonyms: Rorb; RAR-related orphan receptor beta; hs; Nr1; Ror; RZRB; hstp; Nr1f2; RZR-b; Rorbeta; RZR-beta; nuclear receptor ROR-beta; nuclear receptor RZR-beta; nuclear receptor subfamily 1 group F member 2; retinoid-related orphan receptor-beta
• Gene ID: 225998
• mRNA Refseq: NM_146095
• Protein Refseq: NP_666207
• UniProt ID: Q8R1B8