Recombinant Mouse Rtn4r Protein (Cys27-Ser447), C-His tagged

• Cat.No.: Rtn4r-6756M
• Product Overview: Recombinant mouse Rtn4r (Cys27-Ser447) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Description: Enables chondroitin sulfate binding activity; heparin binding activity; and neuregulin receptor activity. Involved in several processes, including corpus callosum development; negative regulation of neuron projection development; and neuronal signal transduction. Acts upstream of or within axonogenesis. Located in several cellular components, including axonal growth cone; dendritic shaft; and neuronal cell body. Is integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; forelimb bud; intestine; male reproductive gland or organ; and nervous system. Human ortholog (s) of this gene implicated in schizophrenia. Orthologous to human RTN4R (reticulon 4 receptor).
• Source: Mammalian cells
• Species: Mouse
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 46.31 kDa
• Protein Length: Cys27-Ser447
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Rtn4r reticulon 4 receptor [ Mus musculus (house mouse) ]
• Official Symbol: Rtn4r
• Synonyms: RTN4R; reticulon 4 receptor; reticulon-4 receptor; nogo receptor; Nogo-66 receptor; NgR; NgR1; NOGOR
• Gene ID: 65079
• mRNA Refseq: NM_022982
• Protein Refseq: NP_075358
• UniProt ID: Q99PI8