Recombinant Mouse Setd3 Protein, Myc/DDK-tagged

• Cat.No.: Setd3-5799M
• Product Overview: Purified recombinant protein of mouse full-length SET domain containing 3 (cDNA clone MGC:28544 IMAGE:4195130), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 90.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Setd3 SET domain containing 3 [ Mus musculus (house mouse) ]
• Official Symbol: Setd3
• Synonyms: Setd3; SET domain containing 3; D12Ertd771; D12Ertd771e; 2610102I01Rik; 2610305M23Rik; 6030490B17Rik; actin-histidine N-methyltransferase; SET domain-containing protein 3; endothelial differentiation inhibitory protein D10; histone-lysine N-methyltransferase setd3; EC 2.1.1.85
• Gene ID: 52690
• mRNA Refseq: NM_028262
• Protein Refseq: NP_082538
• UniProt ID: Q91WC0