Recombinant Mouse Smpd4 Protein, His-tagged

• Cat.No.: Smpd4-2087M
• Product Overview: Recombinant Mouse Smpd4 Protein (Met1-Phe185) with N-His tag was expressed in E. coli.

Specification

• Description: Enables sphingomyelin phosphodiesterase activity. Involved in cellular response to tumor necrosis factor; ceramide biosynthetic process; and sphingomyelin catabolic process. Acts upstream of or within in utero embryonic development. Located in endoplasmic reticulum; nuclear envelope; and sarcolemma. Is expressed in cranium; hemolymphoid system; nervous system; respiratory system; and urinary system. Orthologous to human SMPD4 (sphingomyelin phosphodiesterase 4).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.6 kDa
  Accurate Molecular Mass: 23 kDa
• Protein length: Met1-Phe185
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Smpd4 sphingomyelin phosphodiesterase 4 [ Mus musculus (house mouse) ]
• Official Symbol: Smpd4
• Synonyms: SMPD4; sphingomyelin phosphodiesterase 4; nSMase3; nSMase-3; neutral sphingomyelinase 3; neutral sphingomyelinase III; neutral membrane (neutral sphingomyelinase-3); mKIAA1418; 4122402O22Rik
• Gene ID: 77626
• mRNA Refseq: NM_001164609
• Protein Refseq: NP_001158081
• UniProt ID: Q6ZPR5