Recombinant Mouse Smyd2 Protein, Myc/DDK-tagged
Cat.No. : | Smyd2-5986M |
Product Overview : | Purified recombinant protein of mouse full-length SET and MYND domain containing 2 (Smyd2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 49.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Smyd2 SET and MYND domain containing 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Smyd2 |
Synonyms : | SMYD2; SET and MYND domain containing 2; N-lysine methyltransferase SMYD2; histone methyltransferase SMYD2; SET and MYND domain-containing protein 2; KMT3C; Zmynd14; 4930402C15; 1110020E07Rik |
Gene ID : | 226830 |
mRNA Refseq : | NM_026796 |
Protein Refseq : | NP_081072 |
UniProt ID : | Q8R5A0 |
Products Types
◆ Recombinant Protein | ||
SMYD2-8507M | Recombinant Mouse SMYD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMYD2-049H | Active Recombinant Human SMYD2 Protein, His/SUMO-tagged | +Inquiry |
SMYD2-019H | Active Recombinant Human SMYD2 Protein, His/SUMO-tagged | +Inquiry |
SMYD2-2063H | Recombinant Human SMYD2 Protein, MYC/DDK-tagged | +Inquiry |
SMYD2-5289R | Recombinant Rat SMYD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SMYD2-705HCL | Recombinant Human SMYD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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