Recombinant Mouse Steap3 Protein, Myc/DDK-tagged

• Cat.No.: Steap3-6178M
• Product Overview: Purified recombinant protein of mouse full-length STEAP family member 3 (Steap3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Also mediates reduction of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 54.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Steap3 STEAP family member 3 [ Mus musculus (house mouse) ]
• Official Symbol: Steap3
• Synonyms: Steap3; STEAP family member 3; pHyd; Tsap6; pHyde; 1010001D01Rik; metalloreductase STEAP3; dudulin 2; protein nm1054; six-transmembrane epithelial antigen of prostate 3; tumor suppressor-activated pathway protein 6; EC 1.16.1.-
• Gene ID: 68428
• mRNA Refseq: NM_001085409
• Protein Refseq: NP_001078878
• UniProt ID: Q8CI59