Recombinant Mouse Syt1 Protein, Myc/DDK-tagged

• Cat.No.: Syt1-6256M
• Product Overview: Purified recombinant protein of mouse full-length synaptotagmin I (Syt1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
• Molecular Mass: 47.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Syt1 synaptotagmin I [ Mus musculus (house mouse) ]
• Official Symbol: Syt1
• Synonyms: SYT1; synaptotagmin I; synaptotagmin-1; p65; synaptotagmin 1; SytI; AW124717; G630098F17Rik
• Gene ID: 20979
• mRNA Refseq: NM_009306
• Protein Refseq: NP_033332
• UniProt ID: P46096