| Description : |
Predicted to enable co-receptor binding activity and transferrin receptor activity. Acts upstream of or within iron ion homeostasis. Part of HFE-transferrin receptor complex. Is expressed in liver lobe; mesonephros; and urinary system. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (transferrin receptor 2). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
103.2 kDa |
| Protein Length : |
798 |
| AA Sequence : |
MEQRWGLLRRVQQWSPRPSQTIYRR VEGPQLEHLEEEDREEGAELPAQFC PMELKGPEHLGSCPGRSIPIPWAAA GRKAAPYLVLITLLIFTGAFLLGYV AFRGSCQACGDSVLVVDEDVNPEDS GRTTLYWSDLQAMFLRFLGEGRMED TIRLTSLRERVAGSARMATLVQDIL DKLSRQKLDHVWTDTHYVGLQFPDP AHANTLHWVDADGSVQEQLPLEDPE VYCPYSATGNATGKLVYAHYGRSED LQDLKAKGVELAGSLLLVRVGITSF AQKVAVAQDFGAQGVLIYPDPSDFS QDPHKPGLSSHQAVYGHVHLGTGDP YTPGFPSFNQTQFPPVESSGLPSIP AQPISADIADQLLRKLTGPVAPQEW KGHLSGSPYRLGPGPDLRLVVNNHR VSTPISNIFACIEGFAEPDHYVVIG AQRDAWGPGAAKSAVGTAILLELVR TFSSMVSNGFRPRRSLLFISWDGGD FGSVGATEWLEGYLSVLHLKAVVYV SLDNSVLGDGKFHAKTSPLLVSLIE NILKQVDSPNHSGQTLYEQVALTHP SWDAEVIQPLPMDSSAYSFTAFAGV PAVEFSFMEDDRVYPFLHTKEDTYE NLHKMLRGRLPAVVQAVAQLAGQLL IRLSHDHLLPLDFGRYGDVVLRHIG NLNEFSGDLKERGLTLQWVYSARGD YIRAAEKLRKEIYSSERNDERLMRM YNVRIMRVEFYFLSQYVSPADSPFR HIFLGQGDHTLGALVDHLRMLRADG SGAASSRLTAGLGFQESRFRRQLAL LTWTLQGAANALSGDVWNIDNNF |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
