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Recombinant Mouse Tlr5 protein, His & GST-tagged

Cat.No. : Tlr5-2077M
Product Overview : Recombinant Mouse Tlr5 aa. (Lys327~Glu646 (Accession # Q9JLF7)) fused with N-terminal His & GST tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 66.2kDa
Protein length : Lys327~Glu646 (Accession # Q9JLF7)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Characteristic : The isoelectric point is 5.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : Tlr5 toll-like receptor 5 [ Mus musculus (house mouse) ]
Official Symbol : Tlr5
Synonyms : Pccb; propionyl Coenzyme A carboxylase, beta polypeptide; R74805; AI314687; 1300012P06Rik; propionyl-CoA carboxylase beta chain, mitochondrial; PCCase subunit beta; propanoyl-CoA:carbon dioxide ligase subunit beta
Gene ID : 53791
mRNA Refseq : NM_016928.3
Protein Refseq : NP_058624.2
UniProt ID : Q9JLF7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does TLR5 contribute to the modulation of gut microbiota and intestinal homeostasis? 10/19/2021

TLR5 helps regulate gut microbiota composition, maintaining intestinal health and preventing dysbiosis.

What role does TLR5 play in the defense against bacterial infections, particularly in the gut? 03/03/2021

TLR5 plays a crucial role in protecting against gut bacterial infections by recognizing flagellin and initiating immune defense.

What is the impact of TLR5 dysfunction on inflammatory bowel diseases like Crohn's disease and ulcerative colitis? 02/27/2021

Dysfunctional TLR5 can contribute to inflammatory bowel diseases, affecting gut inflammation and immune responses.

What are the mechanisms by which TLR5 modulates the inflammatory response and cytokine production? 08/08/2020

TLR5 modulates inflammation, influencing cytokine production and the body's response to infection.

How does TLR5 (Toll-Like Receptor 5) recognize bacterial flagellin and initiate immune responses? 06/20/2020

TLR5 detects bacterial flagellin, triggering signaling pathways that activate immune responses against infections.

How do alterations in TLR5 expression or function affect susceptibility to gastrointestinal infections and disorders? 11/15/2019

Variations in TLR5 function can alter susceptibility to gastrointestinal infections and related disorders.

How does TLR5 influence the development of systemic immunity following exposure to pathogens? 01/24/2019

TLR5 is involved in developing systemic immunity, enhancing the body's overall defense against pathogens.

Customer Reviews (3)

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Reviews
07/29/2022

    Outstanding protein-protein interaction studies, vital for our experiments.

    07/24/2019

      Accurate protein structural analysis, a cornerstone of our investigations.

      02/02/2018

        High-quality protein characterization, fundamental for our research.

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