"Tnfsf18" Related Products


Recombinant Mouse Tnfsf18 protein, Fc-tagged

Cat.No.: Tnfsf18-19M
Product Overview: Recombinant Mouse Tnfsf18(Thr 47 - Ser 173) fused with human IgG1 Fc tag at the N-terminus was expressed in HEK293.
Description: Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Source: HEK293
Species: Mouse
Tag : Fc
Form: Lyophilized from 0.22 μm filtered solution in 50 mM Tris,100 mM Glycine,pH7.5. Normally trehalose is added as protectant before lyophilization.
Molecular Mass: The protein has a calculated MW of 41.4 kDa. As a result of glycosylation, The protein migrates as 45 kDa under reducing (R) condition and 80-100 kDa under non-reducing (NR) condition on SDS-PAGE gel.
Protein length: Thr 47 - Ser 173
Endotoxin: Less than 1.0 EU per μg by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
4-8 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Gene Name: Tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 [ Mus musculus ]
Official Symbol: Tnfsf18
Synonyms: TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18; GITR ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced-tumor necrosis factor receptor ligand; Gitrl;
Gene ID: 240873
mRNA Refseq: NM_183391
Protein Refseq: NP_899247
UniProt ID: Q7TS55

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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