Recombinant Mouse Tnfsf18 protein, Fc-tagged
Cat.No. : | Tnfsf18-19M |
Product Overview : | Recombinant Mouse Tnfsf18 (Thr47-Ser173) protein was fused to human IgG1 Fc tag at N-terminus and expressed in human 293 cells (HEK293). |
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Description : | Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18/GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18/GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B. |
Source : | HEK293 |
Species : | Mouse |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Thr47 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 41.4 kDa. As a result of glycosylation, the protein migrates as 45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | Thr47-Ser173 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Tnfsf18 |
Official Symbol : | Tnfsf18 |
Synonyms : | TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18; GITR ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced-tumor necrosis factor receptor ligand; Gitrl |
Gene ID : | 240873 |
mRNA Refseq : | NM_183391 |
Protein Refseq : | NP_899247 |
UniProt ID : | Q7TS55 |
Products Types
◆ Recombinant Protein | ||
TNFSF18-4689R | Recombinant Rhesus Macaque TNFSF18 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF18-38H | Active Recombinant Human TNFSF18 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
TNFSF18-640H | Recombinant Human TNFSF18 Protein (Glu52-Ser177), His-tagged | +Inquiry |
TNFSF18-442T | Active Recombinant Human TNFSF18 Protein (126 aa) | +Inquiry |
TNFSF18-667H | Recombinant Human TNFSF18 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFSF18-890HCL | Recombinant Human TNFSF18 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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