Recombinant Mouse Tpo Protein, His-tagged

• Cat.No.: Tpo-474M
• Product Overview: Recombinant Mouse Tpo Protein (His402-Val558) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: His402-Val558
• Description: This gene encodes a membrane-bound glycoprotein. The encoded enzyme plays a central role in thyroid gland function. The enzyme functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mice with homozygous missense mutations in this gene exhibit hypothyroid dwarfism and hearing impairment.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 19.5 kDa
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Tpo thyroid peroxidase [ Mus musculus (house mouse) ]
• Official Symbol: Tpo
• Synonyms: Tpo; thyroid peroxidase; EC 1.11.1.8
• Gene ID: 22018
• mRNA Refseq: NM_009417
• Protein Refseq: NP_033443
• UniProt ID: P35419