Recombinant Mouse Ube2d1 Protein, Myc/DDK-tagged

• Cat.No.: Ube2d1-6782M
• Product Overview: Purified recombinant protein of mouse full-length ubiquitin-conjugating enzyme E2D 1 (Ube2d1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 16.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ube2d1 ubiquitin-conjugating enzyme E2D 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ube2d1
• Synonyms: UBE2D1; ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog (yeast); ubiquitin-conjugating enzyme E2 D1; E2(17)KB 1; ubiquitin-protein ligase D1; ubiquitin carrier protein D1; ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; UBCH5; MGC28550
• Gene ID: 216080
• mRNA Refseq: NM_145420
• Protein Refseq: NP_663395
• UniProt ID: P61080