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Recombinant Mouse Umod Protein, His/GST-tagged

Cat.No.: Umod-601M
Product Overview: Recombinant Mouse Umod(Glu335~Ser590) fused with His/GST tag at N-terminal was expressed in E. coli.
Description: This gene encodes a glycoprotein that is the most abundant protein in mammalian urine under physiological conditions. It is synthesized in the kidney as a glycosyl-phosphatidylinositol anchored protein and released into urine as a soluble form by proteolytic cleavage. It is thought to regulate water and salt balance in the thick ascending limb of Henle and to protect against urinary tract infection and calcium oxalate crystal formation. In mouse deficiency of this gene is associated with increased susceptibility to bacterial infections and formation of calcium crystals in kidneys. Alternative splicing results in multiple transcript variants.
Source: E. coli
Species: Mouse
Tag : His/GST
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 58.72kDa
Protein length: Glu335~Ser590
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 92%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: Umod uromodulin [ Mus musculus ]
Official Symbol: Umod
Synonyms: UMOD; uromodulin; THP; Tamm-Horsfall protein; Tamm-Horsfall glycoprotein; tamm-Horsfall urinary glycoprotein; urehr4; uromucoid; MGC14034;
Gene ID: 22242
mRNA Refseq: NM_009470
Protein Refseq: NP_033496
UniProt ID: Q91X17

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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