Recombinant Mouse Umod Protein, Myc/DDK-tagged

• Cat.No.: Umod-6833M
• Product Overview: Purified recombinant protein of mouse full-length uromodulin (Umod), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a glycoprotein that is the most abundant protein in mammalian urine under physiological conditions. It is synthesized in the kidney as a glycosyl-phosphatidylinositol anchored protein and released into urine as a soluble form by proteolytic cleavage. It is thought to regulate water and salt balance in the thick ascending limb of Henle and to protect against urinary tract infection and calcium oxalate crystal formation. In mouse deficiency of this gene is associated with increased susceptibility to bacterial infections and formation of calcium crystals in kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 70.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Umod uromodulin [ Mus musculus (house mouse) ]
• Official Symbol: Umod
• Synonyms: UMOD; uromodulin; THP; Tamm-Horsfall protein; Tamm-Horsfall glycoprotein; tamm-Horsfall urinary glycoprotein; urehr4; uromucoid; MGC14034
• Gene ID: 22242
• mRNA Refseq: NM_009470
• Protein Refseq: NP_033496
• UniProt ID: Q91X17