Recombinant Mouse Uri1 Protein, Myc/DDK-tagged

• Cat.No.: Uri1-1919M
• Product Overview: Purified recombinant protein of mouse full-length expressed sequence C80913 (cDNA clone MGC:36045 IMAGE:5374731), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region.
• Molecular Mass: 50.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Uri1 URI1, prefoldin-like chaperone [ Mus musculus (house mouse) ]
• Official Symbol: Uri1
• Synonyms: Uri1; URI1, prefoldin-like chaperone; R; NN; Rmp; NNX3; C80913; unconventional prefoldin RPB5 interactor; RNA polymerase II subunit 5-mediating protein; RPB5-mediating protein; protein phosphatase 1 regulatory subunit 19
• Gene ID: 19777
• mRNA Refseq: NM_011274
• Protein Refseq: NP_035404
• UniProt ID: Q3TLD5