Recombinant Mouse Wrnip1 Protein, Myc/DDK-tagged

• Cat.No.: Wrnip1-7010M
• Product Overview: Purified recombinant protein of Mouse Werner helicase interacting protein 1 (Wrnip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 72.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Wrnip1 Werner helicase interacting protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Wrnip1
• Synonyms: WRNIP1; Werner helicase interacting protein 1; ATPase WRNIP1; werner helicase-interacting protein 1; Werner helicasae interacting protein 1; Werner syndrome homolog interacting protein; WHIP; Wrnip; 4833444L21Rik
• Gene ID: 78903
• mRNA Refseq: NM_030215
• Protein Refseq: NP_084491
• UniProt ID: Q91XU0