Recombinant Mouse Zbtb18 Protein, Myc/DDK-tagged

• Cat.No.: Zbtb18-7051M
• Product Overview: Purified recombinant protein of Mouse zinc finger and BTB domain containing 18 (Zbtb18), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 58.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Zbtb18 zinc finger and BTB domain containing 18 [ Mus musculus (house mouse) ]
• Official Symbol: Zbtb18
• Synonyms: Zbtb18; zinc finger and BTB domain containing 18; RP; RP58; Zfp23; Zfp238; Znf238.; zfp-238; zinc finger and BTB domain-containing protein 18; 58 kDa repressor protein; transcriptional repressor RP58; zinc finger protein 238
• Gene ID: 30928
• mRNA Refseq: NM_013915
• Protein Refseq: NP_038943
• UniProt ID: Q9WUK6