Active Recombinant Murine Wnt3a protein
Cat.No. : | Wnt3a-526M |
Product Overview : | Recombinant Murine Wnt3a(Ser19-Lys352) was expressed in CHO. |
- Specification
- Gene Information
- Related Products
Description : | Protein Wnt-3a is a protein that is encoded by the WNT3A gene. The WNT gene family consists of structurally related genes that encodesecreted signaling proteins. These proteins have been implicated in oncogenesis, adipogenesis, etc. and in several other developmentalprocesses, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family.Mouse Wnt3a shows 96% amino acid identity to human Wnt3a protein. |
Source : | CHO |
Species : | Murine |
Form : | Tris-HCl buffer pH 7.2-7.4, 0.5% CHAPS, 0.1% BSA. |
Bio-activity : | Wnt3a activity has been measured using TCF-based Wnt reporter stable cell line (NIH3T3). 4 ng/mL of Wnt3a generate twenty fold increase of luciferase activity compared to control (buffer without Wnt3a). |
Molecular Mass : | Predicted M.W.: 37 kDa;Actual M.W.: 41 kDa evaluated by SDS-PAGE under reducing conditions; |
Purity : | >75% evaluated by SDS-PAGE under reducing conditions |
Storage : | This preparation can be stored at 4 centigrade for 6 months; Storage under frozen conditions may decrease activity; avoid freeze-thaw. |
Concentration : | 4 µg/mL |
Gene Name : | Wnt3a wingless-type MMTV integration site family, member 3A [ Mus musculus ] |
Official Symbol : | Wnt3a |
Synonyms : | vt; Wnt-3a; vestigial tail; wingless-related MMTV integration site 3A |
Gene ID : | 22416 |
mRNA Refseq : | NM_009522 |
Protein Refseq : | NP_033548 |
UniProt ID : | P27467 |
Chromosome Location : | 11 B1.3; 11 37.17 Cm |
Pathway : | Basal cell carcinoma, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; Melanogenesis, organism-specific biosystem |
Function : | frizzled binding; protein binding; receptor agonist activity |
Products Types
◆ Recombinant Protein | ||
Wnt3a-1050M | Recombinant Mouse Wnt3a Protein, His-tagged | +Inquiry |
WNT3A-10196M | Recombinant Mouse WNT3A Protein, His (Fc)-Avi-tagged | +Inquiry |
Wnt3a-585M | Recombinant Mouse Wnt3a Protein, His-tagged | +Inquiry |
Wnt3a-56M | Active Recombinant Mouse Wnt3a Protein | +Inquiry |
Wnt3a-586R | Recombinant Rat Wnt3a Protein, His-tagged | +Inquiry |
◆ Lysates | ||
WNT3A-295HCL | Recombinant Human WNT3A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionNo interaction between CDH16 protein and WNT3A protein has been found.
The WNT3A protein plays an important role in embryonic development. It is involved in the formation of multiple embryonic organs, directed cell migration, and the establishment of tissue polarity.
Yes, multiple factors have been found in the WNT signaling pathway that regulate the expression and function of WNT3A protein, including Axin, APC, etc.
The WNT3A protein is in the starting position in the Wnt signaling pathway, and it is able to bind to the Wnt receptor and initiate the signaling cascade.
WNT3A protein is closely related to cancer stem cells. It may be involved in the self-renewal and differentiation regulation of cancer stem cells, which is of great significance for tumor development and treatment.
Clinical research on WNT3A protein is still ongoing. Studies have shown the important role of WNT3A protein in tumors, neurological diseases, bone metabolism diseases, etc., and future research will further explore its application potential in disease diagnosis, treatment and prognosis assessment.
Customer Reviews (3)
Write a reviewThis protein is highly expressed and can efficiently synthesize a large number of target proteins in host cells.
This protein has therapeutic effects on specific disease models and is a promising candidate for new drugs.
The laboratory personnel feedback that the protein is easy to operate, can meet the experimental needs, and has a good cost performance.
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