Recombinant Rabbit IL-8
Cat.No. : | IL8-30R |
Product Overview : | Rabbit IL-8 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
- Specification
- Gene Information
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Description : | Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. |
Source : | Yeast |
Species : | Rabbit |
Form : | Lyophilized |
Molecular Mass : | 9.1 kDa |
AA Sequence : | AVRSLHCRLQ DAQQKSLVLS GTYELKALHL NAENLNQQVV FSMSFVQGEE SNDKIPVALG LRGKNLYLSC VMKDDKPTLQ LESVDPNRYP KKKMEKRFVF NKIEIKDKLE FESAQFPNWY ISTSQTEYMP VFLGNNSGGQ DLIDFSMEFV SS (152) |
Applications : | The Rabbit IL-8 protein can be used in cell culture, as an IL-8 ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | IL8 interleukin 8 [ Oryctolagus cuniculus ] |
Official Symbol : | IL8 |
Synonyms : | IL8; interleukin 8; interleukin-8; PF1; IL-8; RPF1; NAP-1; permeability factor 1; C-X-C motif chemokine 8; neutrophil attractant/activation protein 1; neutrophil attractant/activation protein-1; |
Gene ID : | 100009129 |
mRNA Refseq : | NM_001082293 |
Protein Refseq : | NP_001075762 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionActs as a chemical messenger in the immune system that regulates inflammation and attracts immune cells such as white blood cells.
Regulating tumor microenvironment, promoting tumor growth and metastasis, and can be used in tumor therapy research.
IL8 plays a role in regulating and promoting the migration and activation of inflammatory cells in the inflammatory response.
Can be used to treat inflammatory diseases (such as rheumatoid arthritis, psoriasis), tumors (such as lung cancer, breast cancer) and other diseases.
Yes, IL8 is closely related to immunotherapy, which can enhance the role of the immune system and assist in the treatment of certain diseases.
IL8 is generally prepared by gene recombination technology, and the IL8 gene is introduced into the appropriate expression system, and then expressed and purified.
Customer Reviews (3)
Write a reviewIL8 has good fluorescence and absorption properties.
NIPBL has good stability in different environments and is not easy to degrade.
Through animal models or in vitro experiments to evaluate the mechanism of the recombinant protein in related diseases, we found that the effect is very good.
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