Recombinant Rat Casr Protein (Lys863-Ser1079), N-His tagged

• Cat.No.: Casr-6838R
• Product Overview: Recombinant Rat Casr (Lys863-Ser1079) fused with the N-terminal His tag was expressed in mammalian cells.

Specification

• Description: Enables integrin binding activity; protein kinase binding activity; and transmembrane transporter binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; blood vessel diameter maintenance; and cellular chemical homeostasis. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and neuronal cell body. Used to study cardiomyopathy. Biomarker of atherosclerosis; myocardial infarction; and pulmonary hypertension. Human ortholog (s) of this gene implicated in several diseases, including autosomal dominant hypocalcemia (multiple); hypercalcemia (multiple); hyperparathyroidism (multiple); idiopathic generalized epilepsy 8; and nephrolithiasis (multiple). Orthologous to human CASR (calcium sensing receptor).
• Source: Mammalian cells
• Species: Rat
• Tag: N-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 52.3 kDa
• Protein Length: Lys863-Ser1079
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in TBS, pH 7.5 or lyophilized from TBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Casr calcium-sensing receptor [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Casr
• Synonyms: Casr; calcium-sensing receptor; PCaR1; RaKCaR; extracellular calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); parathyroid Cell calcium-sensing receptor
• Gene ID: 24247
• mRNA Refseq: NM_016996
• Protein Refseq: NP_058692
• UniProt ID: P48442