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Recombinant Rat Hpse protein, His & T7-tagged

Cat.No. : Hpse-707R
Product Overview : Recombinant Rat Hpse aa. (Arg40~Pro188 (Accession # Q71RP1)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Description : Endo-beta-glucuronidase capable of cleaving heparan sulfate involved in the regulation of heparin sulfate proteoglycan function.
Source : E. coli
Species : Rat
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 20.9kDa
Protein length : Arg40~Pro188 (Accession # Q71RP1)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 8.7.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Hpse heparanase [ Rattus norvegicus (Norway rat) ]
Official Symbol : Hpse
Synonyms : Hpse; heparanase; Hep; Hpa; endo-glucoronidase; heparanase-like
Gene ID : 64537
mRNA Refseq : NM_022605.1
Protein Refseq : NP_072127.1
UniProt ID : Q71RP1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of HPSE protein in tumor immune evasion? 11/04/2022

By regulating the tumor microenvironment and the function of immune cells, HPSE protein participates in the process of tumor immune evasion.

Does HPSE protein have potential applications in tumor immunotherapy? 05/26/2022

Yes, the mechanism by which HPSE proteins act in relation to tumor immunotherapy has potential applications in this regard.

How about the fuction of HPSE protein in liver fibrosis? 09/30/2021

The protein plays an important role in liver fibrosis and participates in the regulation of liver tissue fibrosis through mechanisms such as collagen degradation.

How does HPSE protein participate in tumor invasion and metastasis? 08/25/2020

HPSE protein is involved in regulating tumor invasion and metastasis by degrading the basement membrane and promoting cytotoxicity.

What is the role of HPSE protein in collagen degradation, tissue repair and regeneration? 01/24/2020

The protein plays an important role in collagen degradation, tissue repair and regeneration, participates in epithelial-mesenchymal transformation processes, and affects biological processes such as cell migration and remodeling.

What is the role of HPSE protein in inflammatory response? 05/26/2019

HPSE proteins play an important role in the inflammatory response by participating in mechanisms such as extracellular matrix degradation and mediating cytokine production and release.

Customer Reviews (2)

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Reviews
12/08/2019

    The stability of HPSE was still very good under different temperature conditions, indicating that it has excellent thermal stability.

    05/19/2019

      Beacuse high efficiency and wide storage conditions of proteins make the experimental process more convenient and greatly improve the efficiency of scientific research.

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