Recombinant Rhesus Monkey PI16 Protein, hIgG1-tagged

• Cat.No.: PI16-1789R
• Product Overview: Recombinant Rhesus monkey PI16 Protein (XP_014991646 ( aa.29-400)) was expressed in human HEK293 cells with hIgG1 tag.

Specification

• Species: Rhesus macaque
• Source: HEK293
• Tag: Fc
• Protein Length: 29-400 a.a.
• Description: CD363 is a member of the cysteine-rich secretory protein (CRISP) family and is likewise known as CRISP9. PI-16 is a putative serine protease inhibitor and can serve as a binding protein for PSP94 (prostate secretory protein of 94 amino acids) termed PSPBP. Serum levels of PSP94 and PI-16 can reportedly serve as key targets for prostate cancer research. PI-16 is highly expressed by the activated/memory, FoxP3-bright subsets of regulatory T cells. PI-16-positive regulatory T cells expressed uniformly high levels of the chemokine receptors, CCR4 and CCR6, when compared with PI-16-negative T regulatory cells. The results suggest that the CCR4+CCR6+ regulatory T cells are capable of homing to inflammatory sites and regulating effector T cells such as CCR4+CCR6+ Th17-like cells. PI-16 is also expressed by subsets of memory CD4+ and CD8-bright T cells. It is not expressed by B cells or monocytes.
• Form: PBS, pH7.4.
• Purity: > 95 %
• Applications: ELISA; WB; Immunogen
• Storage: -80 centigrade, Avoid freeze/thaw cycle.
• Concentration: 1 mg/mL

Gene Information

• Gene Name: PI16 peptidase inhibitor 16 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: PI16
• Synonyms: PI16; peptidase inhibitor 16; protease inhibitor 16; dJ90K10.5; MGC45378; microseminoprotein; beta binding protein; MSMBBP; PSP94-binding protein; cysteine-rich secretory protein 9; microseminoprotein; beta-binding protein; PSPBP; CRISP9; DKFZp586B1817
• Gene ID: 719301
• mRNA Refseq: XM_015136160.1
• Protein Refseq: XP_014991646