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Recombinant Rhesus Monkey TNFSF18 Protein

Cat.No. : TNFSF18-1814R
Product Overview : Recombinant Rhesus monkey TNFSF18 Protein (Q1PBC4 ( aa.50-177)) was expressed in human HEK293 cells.
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Description : GITRL/TNFSF18 is a member of the tumor necrosis factor (TNF) superfamily which is a ligand for receptor TNFRSF18/AITR/GITR. it regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
Source : HEK293
Species : Rhesus monkey
Form : PBS, pH7.4.
Purity : > 95 %
Applications : WB; ELISA; Immunogen
Storage : -80 centigrade, Avoid freeze/thaw cycle.
Concentration : 1 mg/mL
Gene Name : TNFSF18 TNF superfamily member 18 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : TNFSF18
Synonyms : TNFSF18; tumor necrosis factor (ligand) superfamily; member 18; tumor necrosis factor ligand superfamily member 18; AITRL; hGITRL; TL6; AITR ligand; GITR ligand; activation-inducible TNF-related ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; GITRL; MGC138237;
Gene ID : 678654
mRNA Refseq : NM_001040191.1
Protein Refseq : NP_001035281.1
UniProt ID : Q1PBC4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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