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Cat.No. :	Spike-204V
Product Overview :	Recombinant SARS Coronavirus Spike Glycoprotein Mosaic (S2) protein was expressed in E.coli. Mosaic protein contains the middle section of the Spike protein 408-470, 540-573 amino acids immunodominant regions.
Description :	Spike protein S2: Mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Source :	E.coli
Species :	SARS-CoV
Form :	Liquid. 25mM Tris-HCl, 0.4% sarcosyl, 0.25% Triton X-100 and 50% glycerol.
Molecular Mass :	38 kDa
Purity :	>95% as determined by 10% PAGE (coomassie staining).
Applications :	ELISA, Western blot.
Storage :	Upon arrival, storeat below -18 centigrade.
Shipping :	Dry Ice.
Warning :	For Research Use Only.
Synonyms :	sars2; E2; sars3a