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Recombinant SARS-CoV-2 S Protein, His-tagged

Cat.No. : S-25S
Product Overview : Recombinant 2019-nCoV S Protein NTD is produced by our Mammalian expression system and the target gene encoding Gln14-Asp290 is expressed with a 6His tag at the C-terminus.
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Description : The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source : Human Cells
Species : SARS-CoV-2
Tag : His
Form : Supplied as a 0.2 μm filtered solution of PBS, PH7.4.
AA Sequence : Gln14-Asp290
Endotoxin : Less than 0.1 ng/ug (1 EU/ug).
Shipping : Dry ice/ice packs
Gene Name : S surface glycoprotein [ Severe acute respiratory syndrome coronavirus 2 ]
Official Symbol : S
Synonyms : 2019-nCoV S Protein NTD; N terminal domain
Gene ID : 43740568
Protein Refseq : YP_009724390.1
UniProt ID : P0DTC2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Please let me know the sequence part you deleted or the whole aa region of this peptide 08/09/2023

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