Recombinant Severe acute respiratory syndrome coronavirus 2 ORF8 Protein (F16-I121), His/Flag-tagged

• Cat.No.: ORF8-1394S
• Product Overview: Recombinant Severe acute respiratory syndrome coronavirus 2 6His-ORF8(F16-I121)-Flag protein with a His/Flag tag was expressed in E. coli

Specification

• Species: Severe acute respiratory syndrome coronavirus 2
• Source: E.coli
• Tag: Flag&His
• Protein Length: F16-I121
• Description: Plays a role in modulating host immune response. May act by down-regulating major histocompability complex class I (MHC-I). May inhibit expression of some members of the IFN-stimulated gene (ISG) family including hosts IGF2BP1/ZBP1, MX1 and MX2, and DHX58. Binds to IL17RA receptor, leading to IL17 pathway activation and an increased secretion of pro-inflammatory factors. Contributes to cytokine storm during COVID-19 infection.
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: ORF8 ORF8 protein [ Severe acute respiratory syndrome coronavirus 2 ]
• Official Symbol: ORF8
• Synonyms: ORF8; ORF8 protein
• Gene ID: 43740577
• Protein Refseq: YP_009724396
• UniProt ID: P0DTC8