Recombinant Streptococcus Pyogenes IdeS Protein, His&GST tagged

• Cat.No.: IdeS-50S
• Product Overview: The Streptococcus Pyogenes IdeS Protein, His Tag, GST Tag(KMP4413) is produced in E. coli. A DNA sequence encoding the streptococcus pyogenes IdeS (F8V4V0-1) (Asp30-Asn341) was expressed with the N-terminal polyhistidine-tagged a GST tag at the N-terminus (his-GST)

Specification

• Species: Streptococcus Pyogenes
• Source: E. coli
• Tag: GST&His
• Description: IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus.
• Molecular Mass: 63.1 kDa
• Purification: Affinity purification
• Endotoxin: <1.0 EU/μg determined by the LAL method
• Purity: > 85% determined by SDS-PAGE
• Storage: Aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS, 50% Glycerol, pH7.4
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.

Gene Information

• Synonyms: IdeS