Recombinant Streptococcus Pyogenes IdeS Protein, His tagged

• Cat.No.: IdeS-37S
• Product Overview: The Streptococcus Pyogenes IdeS Protein, His Tag(KMP4414) is produced in E. coli. A DNA sequence encoding the streptococcus pyogenes IdeS (F8V4V0-1) (Asp30-Asn341) was expressed with a polyhistidine tag at the N-terminus.

Specification

• Species: Streptococcus Pyogenes
• Source: E. coli
• Tag: His
• Description: IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus.
• Molecular Mass: 36.2 kDa
• Purification: Affinity purification
• Endotoxin: <1.0 EU/μg determined by the LAL method
• Purity: > 95% determined by SDS-PAGE
• Storage: Aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS, 50% Glycerol, pH6.6
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.

Gene Information

• Synonyms: IdeS