Recombinant Zaire ebolavirus VP40 Protein (N31-K326), His-tagged

• Cat.No.: VP40-1438Z
• Product Overview: Recombinant Zaire ebolavirus 6His-TEV-GG-VP40(N31-K326 end) (H269L) protein with a His tag was expressed in E. coli

Specification

• Species: Zaire Ebola virus
• Source: E.coli
• Tag: His
• Protein Length: N31-K326
• Description: Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: VP40 matrix protein [ Zaire ebolavirus ]
• Official Symbol: VP40
• Synonyms: VP40; matrix protein; matrix protein
• Gene ID: 911825
• Protein Refseq: NP_066245
• UniProt ID: Q05128