Red Active Caspase-8 Staining Kit

• Cat.No.: Kit-2373
• Product Overview: Activation of caspases plays a central role in apoptosis. The Red Active Caspase-8 Staining Kit provides a convenient means for detecting activated caspase-8 in; Living cells. The assay utilizes a caspase-8 inhibitor IETD-FMK conjugated to sulfo-rhodamine (Red-IETD-FMK) as the fluorescent marker. Red-IETD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspase-8 in apoptotic cells.

Specification

• Tag: Non
• Applications: Detection of activated caspase-8 in living cells.
• Storage: -20°C
• Shipping: Gel Pack
• Kit Components: Red-IETD-FMK; Wash Buffer; Z-VAD-FMK
• Target Species: Mammalian
• Detection method: Fluorescence microscopy, fluorescence plate reader(Ex/Em = 540/570 nm) and Flow cytometry
• Features & Benefits: Simple one-step procedure; takes only 1-2 hours; Fast and convenient; The fluorescence label allows detection of activated caspase-8 in apoptotic cells