ccr2
Share
  • Official Full Name
  • chemokine (C-C motif) receptor 2
  • Background
  • This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009] This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
  • Synonyms
  • CCR2; chemokine (C-C motif) receptor 2; CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; C-C chemokine receptor type 2; MCP-1 receptor; monocyte chemotactic protein 1 receptor; monocyte chemoattractant protein 1 receptor; FLJ78302; MGC103828; MGC111760; MGC168006; C-C CKR-2; OTTHUMP00000209948
Cat.#:CCR2-3014MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse CCR2 Protein, His-tagged
+Inquiry
Cat.#:CCR2-705RTag:His
Source (Host):E. coliSpecies:Rhesus Monkey
Product nameRecombinant Rhesus Monkey CCR2 Protein, His-tagged
+Inquiry
Cat.#:CCR2-0689HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR2 Protein, GST-Tagged
+Inquiry
Cat.#:CCR2-135HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR2 Protein
+Inquiry
Cat.#:CCR2-1412HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR2 Protein
+Inquiry
Cat.#:CCR2-190HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR2 Protein
+Inquiry
Cat.#:CCR2-27804THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CCR2
+Inquiry
Cat.#:CCR2-1227RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CCR2 Protein
+Inquiry
Cat.#:CCR2-3494CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CCR2
+Inquiry
Cat.#:CCR2-7696HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CCR2 293 Cell Lysate
+Inquiry
Cat.#:Kit-1150Tag:
Source (Host):Species:
Product nameCCR2 CHO-K1 β-Arrestin GPCR Assay Kit
+Inquiry
Cat.#:Kit-1637Tag:
Source (Host):Species:
Product nameCHO-K1 CCR2 Bioassay Kit
+Inquiry
Cat.#:Kit-1638Tag:
Source (Host):Species:
Product nameCCR2 Total GPCR Internalization Assay Kit
+Inquiry

CCR2 Related Articles

Palacios, BS; Estrada-Capetillo, L; et al. Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile. JOURNAL OF PATHOLOGY 235:515-526(2015).
Srivastava, K; Hu, J; et al. Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth. CANCER CELL 26:880-895(2014).

CCR2 Related Gene Family

GPCRs Chemokines Cytokines