|Official Full Name||carcinoembryonic antigen-related cell adhesion molecule 5|
|Background||CEACAM1 and CEACAM5 belong to the carcinoembryonic antigen (CEA) gene family. It is expressed on cells of epithelial and myeloid origin. CEACAM1 expression is downregulated in many tumors indicating a tumor - suppressive function. The antitumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of antiangiogenic molecules from the cells. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A (A1, A2) and one B domain. While the N, A1 and B domains can also be found in other CEA-family members, the A2 domain of CEACAM1 differs from those found in other CEACAM. CEACAM5 is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is a homodimer. It is a receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.|
|Synonyms||CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100; DKFZp781M2392|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CEACAM5 involved in several pathways and played different roles in them. We selected most pathways CEACAM5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CEACAM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
CEACAM5 has several biochemical functions, for example, GPI anchor binding, identical protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CEACAM5 itself. We selected most functions CEACAM5 had, and list some proteins which have the same functions with CEACAM5. You can find most of the proteins on our site.
|GPI anchor binding||MPPE1; DPEP1; THY1; CEACAM5; VNN1; NIPAL1|
|identical protein binding||CEP57L1; MYBPC3; CLDN10; SH3GL3; MCM6; TP73; ATG101; ADORA2A; DYNLT1A; SCAND1|
|protein homodimerization activity||GLA; TG; WHRN; PVRL1A; TSG101; SQSTM1; PYCARD; TESC; CADM3; WRN|
CEACAM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CEACAM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CEACAM5.
c3; llama single domain; draE; CEACAM1; CEACAM6; afaE3; UQCC2