Recombinant Human CEACAM5 Protein, His\Avi-tagged

• Cat.No.: CEACAM5-194H
• Product Overview: Biotinylated Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 is produced by our Mammalian expression system and the target gene encoding Lys35-Ala685 is expressed with a Avi, 6His tag at the C-terminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: Avi&His
• Protein Length: 35-685 a.a.
• Description: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• AA Sequence: Lys35-Ala685
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: CEACAM5 CEA cell adhesion molecule 5 [ Homo sapiens (human) ]
• Official Symbol: CEACAM5
• Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e
• Gene ID: 1048
• mRNA Refseq: NM_001291484.3
• Protein Refseq: NP_001278413.1
• MIM: 114890
• UniProt ID: P06731