Recombinant Full Length Human CEACAM5 Protein, GST-tagged

Cat.No. : CEACAM5-3274HF
Product Overview : Human CEACAM5 full-length ORF (AAH34671.1, 1 a.a. - 702 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 103.2 kDa
Protein Length : 702 amino acids
AA Sequence : MESPSAPPHRWCIPWQRLLLTASLL TFWNPPTTAKLTIESTPFNVAEGKE VLLLVHNLPQHLFGYSWYKGERVDG NRQIIGYVIGTQQATPGPAYSGREI IYPNASLLIQNIIQNDTGFYTLHVI KSDLVNEEATGQFRVYPELPKPSIS SNNSKPVEDKDAVAFTCEPETQDAT YLWWVNNQSLPVSPRLQLSNGNRTL TLFNVTRNDSASYKCETQNPVSARR SDSVILNVLYGPDAPTISPLNTSYR SGENLNLSCHAASNPPAQYSWFVNG TFQQSTQELFIPNITVNNSGSYTCQ AHNSDTGLNRTTVTTITVYAEPPKP FITSNNSNPVEDEDAVALTCEPEIQ NTTYLWWVNNQSLPVSPRLQLSNDN RTLTLLSVTRNDVGPYECGIQNELS VDHSDPVILNVLYGPDDPTISPSYT YYRPGVNLSLSCHAASNPPAQYSWL IDGNIQQHTQELFISNITEKNSGLY TCQANNSASGHSRTTVKTITVSAEL PKPSISSNNSKPVEDKDAVAFTCEP EAQNTTYLWWVNGQSLPVSPRLQLS NGNRTLTLFNVTRNDARAYVCGIQN SVSANRSDPVTLDVLYGPDTPIISP PDSSYLSGANLNLSCHSASNPSPQY SWRINGIPQQHTQVLFIAKITPNNN GTYACFVSNLATGRNNSIVKSITVS ASGTSPGLSAGATVGIMIGVLVGVA LI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 [ Homo sapiens ]
Official Symbol : CEACAM5
Synonyms : CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100; DKFZp781M2392;
Gene ID : 1048
mRNA Refseq : NM_004363
Protein Refseq : NP_004354
MIM : 114890
UniProt ID : P06731

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CEACAM5 levels be used to detect cancer in its early stages? 03/28/2021

CEACAM5 can be a helpful marker, but it is not typically used for early cancer detection.

Are there any limitations to using CEACAM5 as a cancer marker? 04/07/2018

CEACAM5 is not specific to a single cancer type and may also be elevated in non-cancerous conditions.

What other medical conditions or diseases can cause an increase in CEACAM5 levels? 02/14/2018

Conditions like hepatitis, pancreatitis, and some non-cancerous gastrointestinal diseases can also elevate CEACAM5 levels.

How is CEACAM5 protein used in cancer treatment monitoring? 12/27/2016

CEACAM5 levels are monitored to assess the effectiveness of cancer treatment and to detect cancer recurrence.

Can CEACAM5 levels vary between different individuals, and if so, why? 12/03/2016

Yes, CEACAM5 levels can vary between individuals due to genetic factors and other individual-specific variables.

Customer Reviews (3)

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Reviews
03/03/2020

    CEACAM5 protein has exhibited remarkable performance in Western Blotting experiments.

    08/06/2019

      This enhanced visibility and distinctness of the protein bands greatly aided in the accurate analysis and interpretation of my Western Blotting results.

      09/23/2018

        Its reliability, versatility, and ability to deliver clear and reliable results make it a top choice for researchers in need of a high-quality protein for their experiments.

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