|Official Full Name||Fc fragment of IgG, low affinity IIa, receptor (CD32)|
|Background||This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.|
|Synonyms||FCGR2A; Fc fragment of IgG, low affinity IIa, receptor (CD32); CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
FCGR2A involved in several pathways and played different roles in them. We selected most pathways FCGR2A participated on our site, such as Phagosome, Osteoclast differentiation, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Phagosome||ATP6V0A1B; HLA-DQA2; HLA-G; CALRL2; SFTPD; ATP6V1C2; BMA1; TUBA1B; CTSLA; TUBB2|
|Osteoclast differentiation||TNFRSF11B; LILRB5; CYBA; FCGR2A; FYN; MAP2K1; PIK3CG; LILRA2; TGFB2; PPP3CC|
|Platelet activation||ITGB1; PIK3CG; PRKCZ; F2RL3; MYL12B; PLCB4; AKT1; TLN1; FGB; PIK3CB|
|Fc gamma R-mediated phagocytosis||AKT1; PRKCG; PAK1; MARCKSL1; PIK3CA; GSN; CFL1; AKT2; WASF2; BIN1|
|Leishmaniasis||PTGS2; HLA-DQA1; RELA; ITGB2; FCGR1A; HLA-DMA; IL12A; NFKB1; FCGR3; MYD88|
|Staphylococcus aureus infection||ITGB2; H2-AB1; HLA-DRB1; FCGR3A; ICAM1; Hc; FCGR3B; FCGR2C; FPR2; MBL1|
|Tuberculosis||CAMK2A; HLA-DQA1; IL12A; CLEC7A; CASP9; Itgam&Itgb2; CD74; STAT1; HLA-DOB; KSR1|
|Systemic lupus erythematosus||HIST1H4K; HLA-DOB; HIST1H2AI; H3F3C; HLA-DRA; HIST2H2BE; H2-AB1; HIST2H3A; C8A; HLA-DPA1|
FCGR2A has several biochemical functions, for example, IgG binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR2A itself. We selected most functions FCGR2A had, and list some proteins which have the same functions with FCGR2A. You can find most of the proteins on our site.
|IgG binding||CD247L; FCGR3A; FCGR2B; FCGR2A; FCGR1A; FCGRT; cgr2b; FCER1G; FCGR1B; PIP|
|protein binding||DNAJC7; PASK; TNNT1; RNF14; CHMP4A; HSFX1; RGS2; UBLCP1; C11orf65; UTP14A|
FCGR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGR2A.
UBQLN1; UBQLN1; drozitumab; CRP; SYK