fcgr2a
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  • Official Full Name
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Background
  • This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • FCGR2A; Fc fragment of IgG, low affinity IIa, receptor (CD32); CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
Cat.#:FCGR2A-383HTag:His & Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A Protein (H167), His & Avi-tagged, Biotinylated
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Cat.#:FCGR2A-384HTag:His & Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A Protein (R167) (Ala 36 - Ile 218), His & Avi-tagged, Biotinylated
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Cat.#:FCGR2A-932RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat FCGR2A Protein (Met1-Leu216), His-tagged
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Cat.#:FCGR2A-3990HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCGR2A Protein
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Cat.#:FCGR2A-3992HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCGR2A Protein, GST-tagged
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Cat.#:FCGR2A-1136HTag:His/AVI
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A, His & AVI tagged
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Cat.#:FCGR2A-12819HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FCGR2A, GST-tagged
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Cat.#:FCGR2A-161HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human FCGR2A, His-tagged
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Cat.#:FCGR2A-259HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A, His-tagged, Biotinylated
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Cat.#:FCGR2A-260HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A Protein, His-tagged, Biotinylated
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Cat.#:FCGR2A-2963HTag:His/AVI
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A, His & AVI Tagged, Biotinylated, 167 His
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Cat.#:FCGR2A-2964HTag:His/AVI
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A, His & AVI Tagged, Biotinylated, 167 Arg
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Cat.#:FCGR2A-3074HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human FCGR2A, His tagged
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Cat.#:FCGR2A-3130HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A, Fc tagged
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Cat.#:FCGR2A-352HTag:His/AVI
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A protein, His & Avi-tagged, Biotinylated
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Cat.#:FCGR2A-399HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human FCGR2A, His-tagged
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Cat.#:FCGR2A-649HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A, His tagged
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Cat.#:FCGR2A-7236HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FCGR2A, His-tagged
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Cat.#:FCGR2A-2305RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FCGR2A Protein
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Cat.#:Fcgr2a-4939RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Fcgr2a protein, Fc-tagged
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Cat.#:FCGR2A-270CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus Monkey FCGR2A protein, His-tagged
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Cat.#:FCGR2A-2973CTag:His/AVI
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FCGR2A, His & AVI tagged
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Cat.#:FCGR2A-4107CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FCGR2A, His tagged
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Cat.#:FCGR2A-4108CTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus Fc Fragment Of LgG, Low Affinity LIa, Receptor (CD32), AVI-tagged
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Cat.#:FCGR2A-519CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FCGR2A Protein, His-tagged
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Cat.#:FCGR2A-1675RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FCGR2A Protein, His-tagged
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Cat.#:FCGR2A-4111CTag:His
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus FCGR2A protein, His-tagged
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Cat.#:FCGR2A-001HCLTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human FCGR2A cell lysate
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Cat.#:FCGR2A-1996HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCGR2A cell lysate
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Cat.#:FCGR2A-678HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human FCGR2A cell lysate
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Cat.#:FCGR2A-1926CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FCGR2A cell lysate
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Involved Pathway

FCGR2A involved in several pathways and played different roles in them. We selected most pathways FCGR2A participated on our site, such as Phagosome, Osteoclast differentiation, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
FCGR4; TUBA1L; COLEC12; ATP6V1A; Itgam&Itgb2; TLR2; ATP6V1C1; ACTB2; RAB5C; ATP6V1BA
Osteoclast differentiation
IFNGR1; PIK3R5; RAC1; TNFRSF11A; MAP3K7; FHL2; NFKB2; TGFBR1; PIK3CA; MAPK13
Platelet activation
APBB1IP; ITPR3; PLA2G4D; MAPK11; VAMP8; GNAQ; COL27A1; GP1BA; TBXA2R; MAPK3
Fc gamma R-mediated phagocytosis
PTPRC; WASF3; PRKCE; VASP; PLD1; BIN1; PRKCA; SCIN; MAPK3; MYO10
Leishmaniasis
NOS2; MARCKSL1; IL12B; PTGS2; MAPK3; HLA-DRB3; ELK1; STAT1; NFKB1; NCF4
Staphylococcus aureus infection
FCGR1; ICAM1; FCGR2A; HLA-DRB3; HLA-DPA1; C3; CFH; C1RA; H2-AB1; cgr2b
Tuberculosis
CAMK2B; CARD9; RELA; RHOA; KSR1; IFNA21; CALM4; CASP10; MAPK11; HLA-DRB3
Systemic lupus erythematosus
C2; C8G; HIST1H2BO; HIST1H4A; CD28; HLA-DQA1; HLA-DQB1; HIST1H2BN; HLA-DRB4; HIST1H4F

Protein Function

FCGR2A has several biochemical functions, for example, IgG binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR2A itself. We selected most functions FCGR2A had, and list some proteins which have the same functions with FCGR2A. You can find most of the proteins on our site.
Function
Related Protein
Function IgG binding
Related Protein FCGR1B; FCGR3B; FCGR3A; FCER1G; FCGR2A; FCGR1; FCGR1A; FCGR2C; CD247L; FCGRT
Function protein binding
Related Protein HOOK3; NME3; NOS2; Fgf15; PPP1R12B; NFE2; LRFN2; FNIP1; HIST1H2AM; EIF4A3

Interacting Protein

FCGR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGR2A.
UBQLN1; UBQLN1; drozitumab; CRP; SYK

FCGR2A Related Articles

Carmona, FD; Martin, J; et al. Genetics of vasculitis. CURRENT OPINION IN RHEUMATOLOGY 27:10-17(2015).
Amirkhosravi, A; Boulaftali, Y; et al. CalDAG-GEFI deficiency protects mice from Fc gamma RIIa-mediated thrombotic thrombocytopenia induced by CD40L and beta 2GPI immune complexes. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12:2113-2119(2014).