s100a4
Share
  • Official Full Name
  • S100 calcium binding protein A4
  • Background
  • The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Synonyms
  • S100A4; S100 calcium binding protein A4; 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98; protein S100-A4; protein Mts1; fibroblast-specific protein-1; placental calcium-binding protein; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog);
Cat.#:S100A4-2599RTag:His/Myc
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat S100A4 Protein (2-101 aa), His-Myc-tagged
+Inquiry
Cat.#:S100A4-162HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human S100A4
+Inquiry
Cat.#:S100A4-195HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A4 Protein, His-tagged
+Inquiry
Cat.#:S100A4-201HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100 Calcium Binding Protein A4
+Inquiry
Cat.#:S100A4-2489HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A4, GST-tagged
+Inquiry
Cat.#:S100A4-31367THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A4
+Inquiry
Cat.#:S100A4-3727HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A4, His-tagged
+Inquiry
Cat.#:S100A4-409HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100 Calcium Bbinding Protein A4, His-tagged
+Inquiry
Cat.#:S100A4-70HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human S100A4, Fc tagged
+Inquiry
Cat.#:S100A4-89HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A4
+Inquiry
Cat.#:S100A4-159MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse S100a4, Fc tagged
+Inquiry
Cat.#:S100a4-3542MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100a4, His-tagged
+Inquiry
Cat.#:S100a4-532MTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse S100a4
+Inquiry
Cat.#:S100a4-533MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100a4, His-tagged
+Inquiry
Cat.#:S100A4-5213RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat S100A4 Protein
+Inquiry
Cat.#:S100A4-2120CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle S100A4 protein, His-tagged
+Inquiry
Cat.#:S100a4-5105MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100 calcium Binding Protein A4, His-tagged
+Inquiry
Cat.#:S100A4-2859HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human S100A4 cell lysate
+Inquiry
Cat.#:S100A4-001MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse S100A4 cell lysate
+Inquiry

Protein Function

S100A4 has several biochemical functions, for example, RAGE receptor binding, actin binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A4 itself. We selected most functions S100A4 had, and list some proteins which have the same functions with S100A4. You can find most of the proteins on our site.
Function
Related Protein
Function RAGE receptor binding
Related Protein S100A13; S100P; S100A4; S100A12; S100B; HMGB1; FPR1; HMGB2; S100A9; S100A8
Function actin binding
Related Protein PTK2; PLS3; ALDOA; GC; MYO1F; VPS16; TBCCD1; MYH7; LIMCH1; CALD1
Function calcium ion binding
Related Protein PRF1; THBS3; Shh; MYL9B; HPCAL4; EFCAB3; MYL4; CABP2; DGKG; RAB11FIP4
Function calcium-dependent protein binding
Related Protein MBL1; CALM1; CHP; KCNIP3; A2M; SYT8; RBM22; S100A1; S100PBP; FCN2
Function identical protein binding
Related Protein SUN2; GYPA; PAFAH1B3; GOT2A; IMPA1; HOOK3; UBQLN1; PAK2; EPS15; APOH
Function poly(A) RNA binding
Related Protein YWHAZ; SR140; RPL27A; SNW1; RPS20; DDX49; PFN1; RPLP0; APOBEC3F; PRPF6
Function protein binding
Related Protein POU3F2; ZNF496; CSTF2T; HAAO; MATN4; PLAA; MAPK8IP3; GTF2B; POLR2E; CD46

Interacting Protein

S100A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A4.
TP53; S100B; MDM2; AREGB; BTC

S100A4 Related Articles

Grum-Schwensen, B; Klingelhofer, J; et al. S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance. BMC CANCER 15:-(2015).
Wang, DG; Zhang, JW; et al. Functional expression, characterization and application of the human S100A4 protein. MOLECULAR MEDICINE REPORTS 11:175-181(2015).