vegfc
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  • Official Full Name
  • vascular endothelial growth factor C
  • Background
  • The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]
  • Synonyms
  • VEGFC; vascular endothelial growth factor C; VRP; Flt4-L; FLT4 ligand DHM; vascular endothelial growth factor-related protein; VEGF-C; AW228853
Cat.#:VEGFC-825MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse VEGFC Protein (Ala108-Arg223), His-tagged
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Cat.#:Vegfc-5535MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Vascular Endothelial Growth Factor C
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Cat.#:Vegfc-5536RTag:N/A
Source (Host):Insect cellsSpecies:Rat
Product nameRecombinant Rat Vascular Endothelial Growth Factor C
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Cat.#:Vegfc-635RTag:His
Source (Host):Insect cellsSpecies:Rat
Product nameRecombinant Rat Vascular Endothelial Growth Factor C, His-tagged
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Cat.#:VEGFC-352HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Vascular Endothelial Growth Factor C
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Cat.#:Vegfc-454RTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat Vascular Endothelial Growth Factor C
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Cat.#:VEGFC-131HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human VEGFC Protein, His-tagged
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Cat.#:VEGFC-133HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human VEGFC Protein, His-tagged
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Cat.#:VEGFC-157HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human VEGFC
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Cat.#:VEGFC-211HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human VEGFC, His tagged
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Cat.#:VEGFC-29HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human VEGFC protein, His-tagged
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Cat.#:VEGFC-31451THTag:Fc
Source (Host):Species:Human
Product nameRecombinant Human VEGFC, Fc-tagged
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Cat.#:VEGFC-31733THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VEGFC
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Cat.#:VEGFC-533HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human VEGFC, His-tagged
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Cat.#:VEGFC-604HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VEGFC protein, His & T7-tagged
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Cat.#:VEGFC-8329HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human VEGFC
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Cat.#:VEGFC-18006MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse VEGFC Protein
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Cat.#:Vegfc-605MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Vegfc protein, His-tagged
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Cat.#:Vegfc-46RTag:His
Source (Host):Species:Rat
Product nameRecombinant Rat Vascular Endothelial Growth Factor C, His-tagged
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Cat.#:Vegfc-534RTag:His
Source (Host):Sf 9 Insect cellsSpecies:Rat
Product nameRecombinant Rat Vegfc, His-tagged
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Cat.#:Vegfc-606RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Vegfc protein, His-tagged
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Cat.#:VEGFC-6515RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat VEGFC Protein
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Cat.#:Vegfc-8713RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Vegfc, Fc tagged
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Cat.#:Vegfc-8714RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Vegfc, His tagged
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Cat.#:VEGFC-5153RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey VEGFC Protein, His-tagged
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Cat.#:VEGFC-602DTag:His|T7
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog VEGFC protein, His & T7-tagged
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Cat.#:VEGFC-603CTag:His|T7
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken VEGFC protein, His & T7-tagged
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Cat.#:VEGFC-607RTag:His|GST
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit VEGFC protein, His & GST-tagged
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Cat.#:VEGFC-11752ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish VEGFC
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Cat.#:VEGFC-601CTag:His|T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle VEGFC protein, His & T7-tagged
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Cat.#:Vegfc-5345RTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Rat Vascular Endothelial Growth Factor C, His-tagged
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Cat.#:VEGFC-45HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Vascular Endothelial Growth Factor C, His- tagged
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Cat.#:VEGFC-615HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Vascular Endothelial Growth Factor C, His-tagged
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Cat.#:VEGFC-641HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Vascular Endothelial Growth Factor C
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Cat.#:Vegfc-616RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Vascular Endothelial Growth Factor C
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Cat.#:VEGFC-2768HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human VEGFC cell lysate
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Cat.#:VEGFC-1306RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat VEGFC cell lysate
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Involved Pathway

VEGFC involved in several pathways and played different roles in them. We selected most pathways VEGFC participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with VEGFC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
NGFR; MAPK1; MAP2K2; PLD2; PLA2G12B; GAB1; FLT1; PLA2G2A; MAPK10; PAK6
Rap signaling pathway
FLT4; FGF13; LAT; PRKD2; RAP1A; INS1; ACTG1; RASGRP3; PLCB3; Itgam&Itgb2
Cytokine-cytokine receptor interaction
EDA; KDR; EPOR; CCL27B; IL-8; BMPR1AB; CXCL8; ACVR1BA; IL12BA; IL17RA
PIK-Akt signaling pathway
SOS1; BCL2; FGF5; GNG4; SGK1; Itga10&Itgb1; ATF4; RHEB; PKN2; EIF4E1B
Focal adhesion
ITGB4; DOCK1; LAMA4; COL11A1A; ITGB5; PPP1R12A; MYL12A; MYLK2; ITGA8; LAMA2
TNF signaling pathway
TNFRSF1B; FAS; MAPK11; NFKB1; CXCL3; PIK3CG; CASP7; MAP2K4; DNM1L; MAPK13
Pathways in cancer
TRAF6; CASP9; HDAC1; RASSF5; RET; RBX1; WNT3; PIK3CA; CCNE2; SMAD3

Protein Function

VEGFC has several biochemical functions, for example, chemoattractant activity, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VEGFC itself. We selected most functions VEGFC had, and list some proteins which have the same functions with VEGFC. You can find most of the proteins on our site.
Function
Related Protein
Function chemoattractant activity
Related Protein FGF10; SAA2; MIF; SAA4; CXCL12B; SAA3; VEGFC; HMGB1; CCL15; VHL
Function growth factor activity
Related Protein GSDF; CSF1A; IL7; FGF13A; ENDOU; BMP6; VEGFB; FGF9; FGF12B; NENF
Function protein binding
Related Protein LGALS3; SFPQ; COP1; PTK6; CPEB3; PKD2; EVI5; FAM125A; MAP1LC3B; NKD2
Function vascular endothelial growth factor receptor 3 binding
Related Protein VHL; FIGF; VEGFC

Interacting Protein

VEGFC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VEGFC here. Most of them are supplied by our site. Hope this information will be useful for your research of VEGFC.
FLT4

VEGFC Related Articles

Ma, J; Zhou, D; et al. Keratocytes Create Stromal Spaces to Promote Corneal Neovascularization Via MMP13 Expression. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:-(2014).
Ikeda, K; Oki, E; et al. Intratumoral Lymphangiogenesis and Prognostic Significance of VEGFC Expression in Gastric Cancer. ANTICANCER RESEARCH 34:3911-3915(2014).