Recombinant Human Vascular Endothelial Growth Factor C

• Cat.No.: VEGFC-352H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family and is known to be associated with angiogenesis and lymphangiogenesis in various cancers. VEGF-C plays a key role in the physiology and pathology of many aspects of the cardiovascular system, including vasculogenesis, hematopoiesis, angiogenesis and vascular permeability. VEGF-C may participate in the development and progression of angiogenic diseases.
• Amino Acid Sequence: MAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRR.
• Molecular Weight: The predicted molecular weight of Recombinant Human VEGF-C is Mr 15.4 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 23 kDa.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Formulation: The protein was 0.2 µm filtered and lyophilized from PBS.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
• Synonyms: vascular endothelial growth factor C; VRP; Flt4-L; VEGFC; FLT4 ligand DHM; vascular endothelial growth factor-related protein; VEGF-C; Flt4 ligand; Vascular endothelial growth factor-related protein
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• UniProt ID: P49767
• Chromosome Location: 4q34.3
• Pathway: Bladder cancer; Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; mTOR signaling pathway; Hemostasis; Signaling by VEGF
• Function: growth factor activity; vascular endothelial growth factor receptor 3 binding