arg1
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  • Official Full Name
  • arginase 1
  • Background
  • Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Synonyms
  • ARG1; arginase 1; arginase-1; arginase, liver; type I arginase; liver-type arginase;
Cat.#:ARG1-296HTag:His/MYC
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARG1 Protein, His/MYC-tagged
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Cat.#:ARG1-2582HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARG1 Protein, MYC/DDK-tagged
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Cat.#:Arg1-1132MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse Arg1 Protein, His-tagged
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Cat.#:ARG1-28658THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARG1, His-tagged
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Cat.#:ARG1-3913HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARG1, His tagged
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Cat.#:ARG1-756HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ARG1 protein, GST-tagged
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Cat.#:ARG1-9810HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARG1, His-tagged
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Cat.#:Arg1-1523MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Arg1 protein, His-tagged
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Cat.#:Arg1-1524RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Arg1 protein, His-tagged
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Cat.#:Arg1-3622RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Arg1, His-tagged
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Cat.#:ARG1-4221ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ARG1
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Cat.#:ARG1-2489HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Arginase, Liver, His-tagged
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Cat.#:ARG1-594HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Arginase, Liver
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Cat.#:Arg1-150RTag:N/A
Source (Host):Rat LiverSpecies:Rat
Product nameNative Rat Arginase
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Cat.#:Arg1-8044RTag:N/A
Source (Host):Rat LiverSpecies:Rat
Product nameNative Rat Liver Arginase
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Cat.#:ARG1-1869HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARG1 cell lysate
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Involved Pathway

ARG1 involved in several pathways and played different roles in them. We selected most pathways ARG1 participated on our site, such as Arginine biosynthesis, Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arginine biosynthesis
ARG2; NOS3; GLULB; GOT1; GOT2; NOS2A; ARG1; ACY1; NOS1; GLUD1A
Arginine and proline metabolism
ALDH2.2; ALDH9A1; DAO.1; CKMT1B; ALDH7A1; P4HA1B; CKMT2; PYCR2; CNDP2; SAT1A.2
Metabolic pathways
POLR3G; PRPS1; PCK1; PGP; AK7; PTGES2; SUCLG1; UAP1; NDST2; PIGO
Biosynthesis of amino acids
ALDOCA; PFKP; TPI1B; PAH; BCAT2; CTH; GOT1; PGAM1B; PFKL; PFKM
Amoebiasis
CD1d1; ACTN2; IL-8; COL4A4; C9; SERPINB1C; COL2A1; CTSG; LAMB3; PIK3CD

Protein Function

ARG1 has several biochemical functions, for example, arginase activity, manganese ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARG1 itself. We selected most functions ARG1 had, and list some proteins which have the same functions with ARG1. You can find most of the proteins on our site.
Function
Related Protein
Function arginase activity
Related Protein ARG1; ARG2
Function manganese ion binding
Related Protein HMGCL; LAP3; ABL1; IMPA1; NUDT7; FAM20C; DYRK2; B4GALT1; NUDT16; PPM1AA

Interacting Protein

ARG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARG1.
abh; bec; ESR1; FLOT1; USP53; ATG101; ALDH4A1; midostaurin; GABARAP; MYC; GABARAPL2

ARG1 Related Articles

Wang, JH; Zhao, DM; et al. Toll-Like Receptor 2 Deficiency Shifts PrP106-126-Induced Microglial Activation from a Neurotoxic to a Neuroprotective Phenotype. JOURNAL OF MOLECULAR NEUROSCIENCE 55:880-890(2015).
Bieren, JEV; Volpe, B; et al. Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I. JOURNAL OF IMMUNOLOGY 194:1154-1163(2015).