Recombinant Human ARG1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARG1-2961H
• Product Overview: ARG1 MS Standard C13 and N15-labeled recombinant protein (NP_000036) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.7 kDa
• AA Sequence: MSAKSRTIGIIGAPFSKGQPRGGVE EGPTVLRKAGLLEKLKEQECDVKDY GDLPFADIPNDSPFQIVKNPRSVGK ASEQLAGKVAEVKKNGRISLVLGGD HSLAIGSISGHARVHPDLGVIWVDA HTDINTPLTTTSGNLHGQPVSFLLK ELKGKIPDVPGFSWVTPCISAKDIV YIGLRDVDPGEHYILKTLGIKYFSM TEVDRLGIGKVMEETLSYLLGRKKR PIHLSFDVDGLDPSFTPATGTPVVG GLTYREGLYITEEIYKTGLLSGLDI MEVNPSLGKTPEEVTRTVNTAVAIT LACFGLAREGNHKPIDYLNPPKTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARG1 arginase 1 [ Homo sapiens (human) ]
• Official Symbol: ARG1
• Synonyms: ARG1; arginase, liver; arginase-1; type I arginase; liver-type arginase
• Gene ID: 383
• mRNA Refseq: NM_000045
• Protein Refseq: NP_000036
• MIM: 608313
• UniProt ID: P05089