Il17c
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Official Full Name
interleukin 17C
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Overview
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008] -
Synonyms
IL17C; interleukin 17C; CX2; IL-17C; interleukin-17C; cytokine CX2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Rat
- Zebrafish
- CHO Cells
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian Cell
- Fc
- His
- Avi
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
Il17c involved in several pathways and played different roles in them. We selected most pathways Il17c participated on our site, such as IL17 signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il17c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IL17 signaling pathway | IL17F;TRAF3IP2;IL17C;IL17RC;IL17RE |
Il17c has several biochemical functions, for example, cytokine activity, cytokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il17c itself. We selected most functions Il17c had, and list some proteins which have the same functions with Il17c. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | Il2;TXLNA;IL17D;IFNG1-2;GM13287;BMP7;IL34;LFT2;WNT1 |
| cytokine receptor binding | IFNA13;IL17A/F2;IFNA12;IFNPHI1;IL15L;Ifna11;MIF;IFNPHI2;IFNA14 |
Il17c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il17c here. Most of them are supplied by our site. Hope this information will be useful for your research of Il17c.
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewHigh purity levels.
Potent in anti-fungal assays.
Suitable for receptor binding studies.
Q&As (10)
Ask a questionAnimal models, patient biopsies, and genetic association studies reveal IL17C's role in autoimmune diseases.
Combination cytokine stimulation assays and signaling pathway inhibitors elucidate IL17C's crosstalk.
Xenograft models and tumor growth measurements uncover IL17C's contribution to cancer progression.
Flow cytometry analysis with cell-specific markers characterizes IL17C's impact on immune cell subsets.
Neutralizing antibodies and RNA interference validate IL17C's potential as a therapeutic target.
Infection models, bacterial challenges, and mucosal sampling assess IL17C's role in host defense.
Chemotaxis assays and confocal microscopy study IL17C-mediated immune cell recruitment.
Organoid culture systems and cytokine measurements explore IL17C's impact on epithelial barrier function.
Co-immunoprecipitation and mass spectrometry identify IL17C interactors and signaling molecules.
Comparative functional assays and gene knockout models distinguish IL17C's unique roles.
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