Recombinant Human IL17C protein, His-Avi-tagged
Cat.No. : | IL17C-094H |
Product Overview : | Human IL-17C Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains His19-Val197. |
- Specification
- Gene Information
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Description : | Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 22.6 kDa. |
Protein length : | His19-Val197 |
Endotoxin : | Less than 1 EU per ug by the LAL method. |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | IL17C interleukin 17C [ Homo sapiens (human) ] |
Official Symbol : | IL17C |
Synonyms : | CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884; interleukin 17C; interleukin-17C; MGC138401 |
Gene ID : | 27189 |
mRNA Refseq : | NM_013278.4 |
Protein Refseq : | NP_037410.1 |
MIM : | 604628 |
UniProt ID : | Q9P0M4 |
Products Types
◆ Recombinant Protein | ||
IL17C-441H | Recombinant Human IL17C Protein (Met1-Val197), HIgG1 Fc-tagged | +Inquiry |
Il17c-3500M | Recombinant Mouse Il17c Protein, Myc/DDK-tagged | +Inquiry |
IL17C-358H | Active Recombinant Human IL17C Protein, His-tagged | +Inquiry |
IL17C-2294H | Recombinant Human IL17C Protein, His-tagged | +Inquiry |
Il17c-7980M | Recombinant Mouse Il17c protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL17C-5243HCL | Recombinant Human IL17C 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionAnimal models, patient biopsies, and genetic association studies reveal IL17C's role in autoimmune diseases.
Combination cytokine stimulation assays and signaling pathway inhibitors elucidate IL17C's crosstalk.
Xenograft models and tumor growth measurements uncover IL17C's contribution to cancer progression.
Flow cytometry analysis with cell-specific markers characterizes IL17C's impact on immune cell subsets.
Neutralizing antibodies and RNA interference validate IL17C's potential as a therapeutic target.
Infection models, bacterial challenges, and mucosal sampling assess IL17C's role in host defense.
Chemotaxis assays and confocal microscopy study IL17C-mediated immune cell recruitment.
Organoid culture systems and cytokine measurements explore IL17C's impact on epithelial barrier function.
Co-immunoprecipitation and mass spectrometry identify IL17C interactors and signaling molecules.
Comparative functional assays and gene knockout models distinguish IL17C's unique roles.
Customer Reviews (3)
Write a reviewHigh purity levels.
Potent in anti-fungal assays.
Suitable for receptor binding studies.
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