Recombinant Human IL17C protein, His-tagged
|Product Overview :||Recombinant Human IL17C(Cys36~Val187) fused with His tag at N-terminal was expressed in E. coli.|
- Gene Information
- Related Products
|Description :||The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells.|
|Source :||E. coli|
|Form :||PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300|
|Molecular Mass :||20.7kDa|
|Protein length :||Cys36~Val187|
|Endotoxin :||<1.0EU per 1ug (determined by the LAL method)|
|Purity :||> 95%|
|Applications :||SDS-PAGE; WB; ELISA; IP|
|Stability :||The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.|
|Reconstitution :||Reconstitute in PBS or others.|
|Gene Name :||IL17C interleukin 17C [ Homo sapiens ]|
|Official Symbol :||IL17C|
|Synonyms :||IL17C; interleukin 17C; interleukin-17C; CX2; IL 17C; IL 21; MGC126884; MGC138401; cytokine CX2; IL-21; IL-17C;|
|Gene ID :||27189|
|mRNA Refseq :||NM_013278|
|Protein Refseq :||NP_037410|
|UniProt ID :||Q9P0M4|
|Chromosome Location :||16q24|
|Function :||cytokine activity;|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
Animal models, patient biopsies, and genetic association studies reveal IL17C's role in autoimmune diseases.
Combination cytokine stimulation assays and signaling pathway inhibitors elucidate IL17C's crosstalk.
Xenograft models and tumor growth measurements uncover IL17C's contribution to cancer progression.
Flow cytometry analysis with cell-specific markers characterizes IL17C's impact on immune cell subsets.
Neutralizing antibodies and RNA interference validate IL17C's potential as a therapeutic target.
Infection models, bacterial challenges, and mucosal sampling assess IL17C's role in host defense.
Chemotaxis assays and confocal microscopy study IL17C-mediated immune cell recruitment.
Organoid culture systems and cytokine measurements explore IL17C's impact on epithelial barrier function.
Co-immunoprecipitation and mass spectrometry identify IL17C interactors and signaling molecules.
Comparative functional assays and gene knockout models distinguish IL17C's unique roles.
Customer Reviews (3)Write a review
High purity levels. -
Potent in anti-fungal assays. -
Suitable for receptor binding studies. -
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