Recombinant Mouse Interleukin 17C, His-tagged

• Cat.No.: Il17c-290M
• Product Overview: Recombinant Mouse IL-17C with His-tag was expressed inInsect cell.MW= 22.036 kDa.

Specification

• Species: Mouse
• Source: Insect Cells
• Tag: His
• Description: IL-17C is a member of the IL-17 family, which is comprised of six proteins (IL-17A through IL-17F). IL-17 proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the re-gulation of immune functions. IL-17C has been reported to stimulate the release of TNF-alpha and IL-1β from the monocytic cell line THP-1. IL-17C shares 15% to 30% amino acid sequence identity with the other IL-17 family members. Mouse and human IL-17C share 83% amino acid sequence identity. Mouse IL-17C cDNA encodes a 194 amino acid protein with a putative 14 amino acid signal peptide. The recombinant mouse IL-17C is a disulfide-linked homodimer composed of a 20.2 kDa monomeric subunit.
• Handling Conditions: For best recovery, quick-spin vial prior to opening. Use in a sterile environment.
• Purity: Greater than 97% as determined by SDS-PAGE.
• Endotoxin Level: Less than 0.01 ng/ug cytokine as determined by the LAL assay.
• Bioactivity: Testing in progress.
• Formulation: 20 mM Phosphate, 0.2 M NaCl, pH 6.0, with 1.0% BSA.
• Temperature Limitation: Store at less than or equal to –70°C.

Gene Information

• Gene Name: Il17c interleukin 17C [ Mus musculus ]
• Synonyms: interleukin 17C; IL-17C; MGC175740; Il17c
• Gene ID: 234836
• mRNA Refseq: NM_145834
• Protein Refseq: NP_665833
• Chromosome Location: 8 E1; 8
• Function: cytokine activity