IL27
-
Official Full Name
interleukin 27
-
Background
Interleukin-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (also known as IL-27B) and IL27-p28 (known as IL-30). IL-27 is produced by antigen-presenting cells. IL-27 plays an important function in regulating the activity of B and T lymphocytes. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as IL27R and gp130. -
Synonyms
IL27; interleukin 27; p28; IL30; IL-27; IL-27A; IL27p28; MGC71873; interleukin-27 subunit alpha; IL27-A; IL-27-A; interleukin 30; IL-27 p28 subunit; OTTHUMP00000122516; IL-27 subunit alpha; IL27A;
- IL27 Related Gene Family
- IL27 Related Research Area
- Q&As
- Reviews
Q&As (6)
Ask a questionThe current challenges in the study of Il27 include potential side effects, preparation purity and other challenges.
The potential application of Il27 in tumor immunotherapy and autoimmune diseases is being deeply studied in the scientific research field.
The production of Il27 is related to genetic factors, and the expression level and polymorphism of genes may affect its production and function.
Studies have shown that Il27 may have an anti-inflammatory effect in inflammatory diseases, regulating the degree of inflammatory response.
Current studies have shown that Il27 has potential application value in enhancing anti-tumor immunity and alleviating tumor invasion and metastasis.
Il27 can enhance the activation and proliferation of specific immune cells and regulate the intensity and direction of immune response.
Customer Reviews (3)
Write a reviewThe regulation effect of IL-27 on specific gene expression was detected by Western blot or Real-time PCR. -
IL-27 is a complex cytokine whose function and regulatory mechanisms are still under investigation. -
Immunohistochemistry, immunofluorescence and other techniques can be used to detect the expression and localization of IL-27 in tissues to further understand its function and regulatory mechanism. -
Ask a Question for All IL27 Products
Required fields are marked with *
My Review for All IL27 Products
Required fields are marked with *