IL27
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Official Full Name
interleukin 27
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Overview
Interleukin-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (also known as IL-27B) and IL27-p28 (known as IL-30). IL-27 is produced by antigen-presenting cells. IL-27 plays an important function in regulating the activity of B and T lymphocytes. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as IL27R and gp130. -
Synonyms
IL27; interleukin 27; p28; IL30; IL-27; IL-27A; IL27p28; MGC71873; interleukin-27 subunit alpha; IL27-A; IL-27-A; interleukin 30; IL-27 p28 subunit; OTTHUMP00000122516; IL-27 subunit alpha; IL27A;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Rat
- CHO
- E.coli
- HEK293
- HEK293F
- Human Cell
- Mammalian cells
- Fc
- His
- Avi
- Non
- Other Resource
IL27 involved in several pathways and played different roles in them. We selected most pathways IL27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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IL27 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IL27 itself. We selected most functions IL27 had, and list some proteins which have the same functions with IL27. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
IL27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL27 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL27.
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewThe purity is very high, no impurities.
Biological activity is very strong and can be used in various biological experiments.
Stability is very good, and it will not denaturate at high temperatures.
Q&As (6)
Ask a questionThe current challenges in the study of Il27 include potential side effects, preparation purity and other challenges.
The potential application of Il27 in tumor immunotherapy and autoimmune diseases is being deeply studied in the scientific research field.
The production of Il27 is related to genetic factors, and the expression level and polymorphism of genes may affect its production and function.
Studies have shown that Il27 may have an anti-inflammatory effect in inflammatory diseases, regulating the degree of inflammatory response.
Current studies have shown that Il27 has potential application value in enhancing anti-tumor immunity and alleviating tumor invasion and metastasis.
Il27 can enhance the activation and proliferation of specific immune cells and regulate the intensity and direction of immune response.
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