IL27

  • Official Full Name

    interleukin 27

  • Background

    Interleukin-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (also known as IL-27B) and IL27-p28 (known as IL-30). IL-27 is produced by antigen-presenting cells. IL-27 plays an important function in regulating the activity of B and T lymphocytes. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as IL27R and gp130.
  • Synonyms

    IL27; interleukin 27; p28; IL30; IL-27; IL-27A; IL27p28; MGC71873; interleukin-27 subunit alpha; IL27-A; IL-27-A; interleukin 30; IL-27 p28 subunit; OTTHUMP00000122516; IL-27 subunit alpha; IL27A;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293F
    • Human Cell
    • Tag :
    • Fc
    • His
    • His(C
    • ter)
    • Avi
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL27-881H Recombinant Human IL27 protein, His-tagged CHO His
    Human IL27-335H Recombinant Human IL27 Protein (Met1-Lys229), His-tagged, Biotinylated CHO His
    Human IL27-311H Recombinant Human IL27, His tagged Human Cell His
    Human IL27-124H Active Recombinant Human IL27, HIgG1 Fc-tagged, mutant CHO Fc
    Human IL27-001HCL Recombinant Human IL27 cell lysate CHO N/A
    Human IL27-2306H Recombinant Human IL27 Protein, His-tagged E.coli N-His
    Human IL27-1033H Recombinant Human IL27 Protein, His-tagged CHO N-His
    Human IL27-150H Recombinant Human IL27, Fc tagged Human Cell Fc
    Human IL27-349H Active Recombinant Human IL27, Fc-tagged CHO Fc
    Human IL27-3368H Recombinant Human IL27 protein, His-tagged E.coli His
    Human IL27-123H Active Recombinant Human IL27, HIgG1 Fc-tagged CHO Fc
    Mouse IL27-0234M Recombinant Mouse IL27 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Mouse Il27-2307M Recombinant Mouse Il27 Protein, His-tagged HEK293F N-His
    Mouse IL27-167M Recombinant Mouse p28 Subunit (IL-27) Protein E.coli
    Mouse IL27-1309MCL Recombinant Mouse IL27 cell lysate Human Cell N/A
    Mouse Il27-1675M Recombinant Mouse Il27 Protein, His-tagged E.coli N-His
    Mouse Il27-01M Active Recombinant Mouse Il27 Protein, His-Tagged E.coli His
    Mouse Ebi3&Il27-952M Recombinant Mouse Ebi3&Il27 protein, His-tagged HEK293 His
    Mouse Il27-351M Active Recombinant Mouse Il27, Fc-tagged CHO Fc
    Mouse Il27-554M Recombinant Mouse Il27 Protein, His-tagged E.coli His
    Mouse Ebi3&Il27-406M Active Recombinant Mouse Ebi3&Il27, HIgG1 Fc-tagged CHO Fc
    Mouse IL27-405M Active Recombinant Mouse Interleukin 27, MIgG2a Fc-tagged CHO Fc
    Mouse Il27-506M Active Recombinant Mouse Interleukin 27 E.coli N/A
    Mouse Il27-1309M Active Recombinant Mouse Il27 protein, His-tagged HEK293 His
    Mouse Il27-5204M Recombinant Mouse Il27 Protein E.coli N/A
    Mouse Il27-3518M Recombinant Mouse Il27 Protein HEK293
    Mouse Il27-185M Recombinant Active Mouse IL27 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Rat Il27-1032R Recombinant Rat Il27 Protein, His-tagged HEK293F N-His
    Rat Il27-555R Recombinant Rat Il27 Protein, His-tagged E.coli His
    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    Are there have current difficulties in the study of Il27? 12/23/2022

    The current challenges in the study of Il27 include potential side effects, preparation purity and other challenges.

    Which scientific research fields are deeply studying Il27? 02/21/2022

    The potential application of Il27 in tumor immunotherapy and autoimmune diseases is being deeply studied in the scientific research field.

    Is the production of Il27 related to genetic factors? 09/19/2021

    The production of Il27 is related to genetic factors, and the expression level and polymorphism of genes may affect its production and function.

    Which role of Il27 in inflammatory diseases? 05/17/2021

    Studies have shown that Il27 may have an anti-inflammatory effect in inflammatory diseases, regulating the degree of inflammatory response.

    What the potential applications of recombinant Il27 in cancer therapy? 01/30/2021

    Current studies have shown that Il27 has potential application value in enhancing anti-tumor immunity and alleviating tumor invasion and metastasis.

    What is the effect of Il27 on immune response? 09/27/2020

    Il27 can enhance the activation and proliferation of specific immune cells and regulate the intensity and direction of immune response.

    Customer Reviews (3)

    Write a review
    Reviews
    03/30/2022

      The regulation effect of IL-27 on specific gene expression was detected by Western blot or Real-time PCR. -

      08/05/2020

        IL-27 is a complex cytokine whose function and regulatory mechanisms are still under investigation. -

        05/30/2019

          Immunohistochemistry, immunofluorescence and other techniques can be used to detect the expression and localization of IL-27 in tissues to further understand its function and regulatory mechanism. -

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