Recombinant Human IL27 Protein (Met1-Lys229), His-tagged, Biotinylated IL27-335H

Recombinant Human IL27 Protein (Met1-Lys229), His-tagged, Biotinylated

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human IL27 Protein (Met1-Lys229), His-tagged, Biotinylated

Recombinant Human IL27 Protein (Met1-Lys229), His-tagged, Biotinylated

Online Inquiry

IL27 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : IL27-335H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL27 Protein was produced by CHO Stable Cells expression system. This protein composed of IL27B subunit (NP_005746.2) (Met1-Lys229) and the N-terminally truncated IL27p28 (IL27A) subunit (NP_663634.2) (Phe29-Pro243) linked by an polypeptide linker was fused with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro.
Description : IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells and dendritic cells. IL-27 protein is also referred as the IL-12 p35-related protein, p28, is one subunit of a heterodimeric cytokine complex, and associates with another subunit EBI3 (EBV-induced gene 3), an IL-12 p4-related protein (IL-27B). IL-27 protein is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 protein has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy.
Source : CHO Stable Cells
Species : Human
Tag : His
Predicted N Terminal : Arg 21
Form : Lyophilized from sterile PBS. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human IL27 complex (IL27B & IL27A) consists of 450 amino acids after removal of the signal peptide and has a calculated molecular mass of 56 KDa as estimated in SDS-PAGE under reducing conditions.
Protein length : (IL27A) Phe29-Pro243 & (IL27B) Met1-Lys229
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : IL27 interleukin 27 [ Homo sapiens (human) ]
Official Symbol : IL27
Synonyms : IL27; interleukin 27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28;
Gene ID : 246778
mRNA Refseq : NM_145659
Protein Refseq : NP_663634
MIM : 608273
UniProt ID : Q8NEV9
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry


  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy