Recombinant Mouse Il27 Protein, His-tagged
|Product Overview :||Recombinant Mouse Il27 Protein (Phe29-Ser234+GGGGS*3+Tyr19-Pro228) with N-His tag was expressed in E. coli.|
- Gene Information
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|Description :||Enables interleukin-27 receptor binding activity. Acts upstream of or within positive regulation of defense response to virus by host and regulation of T cell proliferation. Located in extracellular space. Is expressed in decidua; embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and pulmonary tuberculosis. Orthologous to human IL27 (interleukin 27).|
|Source :||E. coli|
|Form :||Freeze-dried powder|
|Molecular Mass :||Predicted Molecular Mass: 49.6 kDa
Accurate Molecular Mass: 60 kDa
|Protein length :||Phe29-Ser234+GGGGS*3+Tyr19-Pro228|
|Purity :||> 90%|
|Applications :||Positive Control; Immunogen; SDS-PAGE; WB.|
|Stability :||The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.|
|Storage Buffer :||20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.|
|Reconstitution :||Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.|
|Gene Name :||Il27 interleukin 27 [ Mus musculus (house mouse) ]|
|Official Symbol :||Il27|
|Synonyms :||IL27; interleukin 27; interleukin-27 subunit alpha; IL27-A; IL-27-A; interleukin 30; IL-27 p28 subunit; IL-27 subunit alpha; p28; Il30; IL-27; IL-27p28;|
|Gene ID :||246779|
|mRNA Refseq :||NM_145636|
|Protein Refseq :||NP_663611|
|UniProt ID :||Q8K3I6|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
The current challenges in the study of Il27 include potential side effects, preparation purity and other challenges.
The potential application of Il27 in tumor immunotherapy and autoimmune diseases is being deeply studied in the scientific research field.
The production of Il27 is related to genetic factors, and the expression level and polymorphism of genes may affect its production and function.
Studies have shown that Il27 may have an anti-inflammatory effect in inflammatory diseases, regulating the degree of inflammatory response.
Current studies have shown that Il27 has potential application value in enhancing anti-tumor immunity and alleviating tumor invasion and metastasis.
Il27 can enhance the activation and proliferation of specific immune cells and regulate the intensity and direction of immune response.
Customer Reviews (3)Write a review
The regulation effect of IL-27 on specific gene expression was detected by Western blot or Real-time PCR. -
IL-27 is a complex cytokine whose function and regulatory mechanisms are still under investigation. -
Immunohistochemistry, immunofluorescence and other techniques can be used to detect the expression and localization of IL-27 in tissues to further understand its function and regulatory mechanism. -
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