Recombinant Dog IL31 Protein (24-159aa)
Cat.No. : | IL31-05D |
Product Overview : | Recombinant Canine IL31 without tag was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
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Description : | IL31, also known as interleukin-31, is a cytokine with an anti-parallel four-helix bundle structure in the gp130/IL-6 cytokine family. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. This protein is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2). This protein is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. |
Source : | HEK293 |
Species : | Dog |
Form : | Liquid |
Molecular Mass : | 15.3 kDa (136aa) |
Protein Length : | 24-159aa |
AA Sequence : | SHMAPTHQLPPSDVRKIILELQPLS RGLLEDYQKKETGVPESNRTLLLCL TSDSQPPRLNSSAILPYFRAIRPLS DKNIIDKIIEQLDKLKFQHEPETEI SVPADTFECKSFILTILQQFSACLE SVFKSLNSGPQ |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE |
Notes : | Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/mL (determined by Bradford assay) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | IL31 interleukin 31 [ Canis lupus familiaris (dog) ] |
Official Symbol : | IL31 |
Synonyms : | IL31; interleukin 31; interleukin-31 |
Gene ID : | 100302725 |
mRNA Refseq : | NM_001165914 |
Protein Refseq : | NP_001159386 |
UniProt ID : | C7G0W1 |
Products Types
◆ Recombinant Protein | ||
Il31-156M | Recombinant Mouse Il31 Protein | +Inquiry |
IL31-284H | Recombinant Human IL31 Protein, StrepII-tagged | +Inquiry |
IL31-189H | Recombinant Active Human IL31 Protein, His-tagged(C-ter) | +Inquiry |
IL31-172M | Recombinant Mouse IL31 Protein | +Inquiry |
IL31-187H | Active Recombinant Human IL31 Protein (Ser24-Thr164), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
IL31-5227HCL | Recombinant Human IL31 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.
IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.
It has a wide range of applications in immune inflammation, dermatology and other research fields.
Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.
IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.
Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.
Customer Reviews (3)
Write a reviewIL31 product has strict quality control and complies with relevant industry standards.
It performs well in biological activity tests.
This protein has high yield and good economic benefits.
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