Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Dog IL31 Protein (24-159aa)

Cat.No. : IL31-05D
Product Overview : Recombinant Canine IL31 without tag was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Description : IL31, also known as interleukin-31, is a cytokine with an anti-parallel four-helix bundle structure in the gp130/IL-6 cytokine family. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. This protein is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2). This protein is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis.
Source : HEK293
Species : Dog
Form : Liquid
Molecular Mass : 15.3 kDa (136aa)
Protein Length : 24-159aa
AA Sequence : SHMAPTHQLPPSDVRKIILELQPLS RGLLEDYQKKETGVPESNRTLLLCL TSDSQPPRLNSSAILPYFRAIRPLS DKNIIDKIIEQLDKLKFQHEPETEI SVPADTFECKSFILTILQQFSACLE SVFKSLNSGPQ
Endotoxin : < 1 EU/μg of protein (determined by LAL method)
Purity : > 90% by SDS-PAGE
Applications : SDS-PAGE
Notes : Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/mL (determined by Bradford assay)
Storage Buffer : Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Gene Name : IL31 interleukin 31 [ Canis lupus familiaris (dog) ]
Official Symbol : IL31
Synonyms : IL31; interleukin 31; interleukin-31
Gene ID : 100302725
mRNA Refseq : NM_001165914
Protein Refseq : NP_001159386
UniProt ID : C7G0W1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What are the advantages of IL31 compared with other therapeutic methods? 07/19/2022

The IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.

What is the action mechanism of IL31? 09/26/2020

IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.

In what research areas is this protein used in the laboratory? 09/09/2020

It has a wide range of applications in immune inflammation, dermatology and other research fields.

How is the clinical research progress of IL31? 01/02/2020

Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.

Are there some challenges in the study of IL31? 10/06/2019

IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.

How to determine the optimal dose of IL31 for treatment? 01/01/2019

Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.

Customer Reviews (3)

Write a review
Reviews
04/22/2022

    IL31 product has strict quality control and complies with relevant industry standards.

    09/26/2021

      It performs well in biological activity tests.

      09/13/2020

        This protein has high yield and good economic benefits.

        Ask a Question for All IL31 Products

        Required fields are marked with *

        My Review for All IL31 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends