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Recombinant Mouse IL31 Protein

Cat.No. : IL31-172M
Product Overview : Recombinant Mouse IL31 Protein without tag was expressed in E. coli.
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  • Gene Information
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Description : Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.
Source : E. coli
Species : Mouse
Bio-activity : No biological activity data is available at this time.
Molecular Mass : Monomer, 15.8 kDa (with 141 amino acids)
AA Sequence : SHTLPVRLLRPSDDVQKIVEELQSL SKMLLKDVEEEKGVLVSQNYTLPCL SPDAQPPNNIHSPAIRAYLKTIRQL DNKSVIDEIIEHLDKLIFQDAPETN ISVPTDTHECKRFILTISQQFSECM DLALKSLTSGAQQATT
Endotoxin : ≤1 EUs/μg, Kinetic LAL (50% confidence)
Purity : ≥95%, Reducing and Non-Reducing SDS PAGE
Stability : 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
1 month when stored at 4 centigrade after reconstituting as directed.
3 months when stored at -20 to -80 centigrade after reconstituting as directed.
Storage : Storage Prior to Reconstitution: -20 centigrade
Storage Buffer : Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Reconstitution : Sterile water at 0.1 mg/mL
Shipping : Room temperature
Instructions : Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.
Gene Name : Il31 interleukin 31 [ Mus musculus (house mouse) ]
Official Symbol : IL31
Synonyms : IL31; interleukin 31; interleukin-31; IL-31; 1700013B14Rik;
Gene ID : 76399
mRNA Refseq : NM_029594
Protein Refseq : NP_083870
UniProt ID : Q6EAL8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the advantages of IL31 compared with other therapeutic methods? 07/19/2022

The IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.

What is the action mechanism of IL31? 09/26/2020

IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.

In what research areas is this protein used in the laboratory? 09/09/2020

It has a wide range of applications in immune inflammation, dermatology and other research fields.

How is the clinical research progress of IL31? 01/02/2020

Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.

Are there some challenges in the study of IL31? 10/06/2019

IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.

How to determine the optimal dose of IL31 for treatment? 01/01/2019

Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.

Customer Reviews (3)

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Reviews
04/22/2022

    IL31 product has strict quality control and complies with relevant industry standards.

    09/26/2021

      It performs well in biological activity tests.

      09/13/2020

        This protein has high yield and good economic benefits.

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