Recombinant Mouse Interleukin 31 Il31-171M

Recombinant Mouse Interleukin 31


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Cat.No. : Il31-171M Optional Service: Optional requirements on this protein
Product Overview : Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues. It was expressed inE.Coli.
Description : IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
Source : E.Coli.
Purity : > 98% (SDS-PAGE; HPLC).
Endotoxin Level : < 0.1 ng/μg of IL-31.
Stabilizer : None.
Formulation : Lyophilized.
Biological Activity : Testing in progress.
Stability : The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-31 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name : Il31 interleukin 31 [ Mus musculus ]
Synonyms : interleukin 31; 1700013B14Rik; Il31
Gene ID : 76399
mRNA Refseq : NM_029594
Protein Refseq : NP_083870
UniProt ID : Q6EAL8
Chromosome Location : 5 F
Function : cytokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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